186
13.2
2017
So much for future technologies and efforts in the field of synthetic biology.
Why should we develop synthetic biology so intensely? Well, for one thing, to achieve
technological progress. Nanotechnology, molecular biology and electronics are our future
technologies, and if we can make electronics much faster with optical methods, we should
strive for this. The steps towards this are already showing great progress, such as picoliter
computer PCR, which would make it possible to place a million or so different DNA mol
ecules on a slide and thus greatly speed up vaccine production, for example. On the other
hand, such efforts have the general advantage of simultaneously merging information stor
age, cellular programming, and also synthesis and microfabrication. Precisely this also
results in a very robust and very environmentally friendly way of producing, as bacteria
and blue-green algae have been demonstrating to us for billions of years. The introduction
of light-controlled protein switches, however, makes it possible to switch each molecule
on and off in a very targeted manner and thus also to achieve a previously unattained preci
sion of synthesis and information processing. In particular, the construction principle pre
vents the technology from taking on a life of its own, something that was not considered
in the 1980s and 1990s when nanotechnology was propagated with living bacteria. On the
other hand, our current technology is not very robustly designed, always has to contend
with raw material problems (today’s electronics, for example, have a shortage of rare
earths), produces dangerous waste (electronic waste) and is very susceptible to disrup
tions, interruptions in world trade and, even more so, to catastrophes or armed conflicts.
Reason enough, therefore, to intensively pursue this molecular technology with the help of
bioinformatics, which has combined three particularly strong exponents of nanotechnol
ogy here for illustration (own proposal: DNA, nanocellulose and light-controlled protein
domains; Dandekar 2013), but has also already achieved very considerable success with
other biomolecules.
13 Life Invents Ever New Levels of Language